Discussion in 'The Howard Stern Show' started by YodaQuiversStern, Jul 18, 2016.
Now her legs aren't muscular enough?
That'll happen when you lay on the floor all day.
That cat has too many eyes, please fix.
The importance of alcohol-induced muscle disease.
Alcohol-induced muscle disease (AIMD) is a composite term to describe any muscle pathology (molecular, biochemical, structural or physiological) resulting from either acute or chronic alcohol ingestion or a combination thereof. The chronic form of AIMD is arguably the most prevalent skeletal muscle disorder in the Western Hemisphere affecting more than 2000 subjects per 100,000 population and is thus much more common than hereditary disorders such as Becker or Duchenne muscular dystrophy. Paradoxically, most texts on skeletal myopathies or scientific meetings covering muscle disease have generally ignored chronic alcoholic myopathy. The chronic form of AIMDs affects 40-60% of alcoholics and is more common than other alcohol-induced diseases, for example, cirrhosis (15-20% of chronic alcoholics), peripheral neuropathy (15-20%), intestinal disease (30-50%) or cardiomyopathy (15-35%). In this article, we summarise the pathological features of alcoholic muscle disease, particularly biochemical changes related to protein metabolism and some of the putative underlying mechanisms. However, the intervening steps between the exposure of muscle to ethanol and the initiation of the cascade of responses leading to muscle weakness and loss of muscle bulk remain essentially unknown. We argue that alcoholic myopathy represents: (a) a model system in which both the causal agent and the target organ is known; (b) a myopathy involving free-radical mediated pathology to the whole body which may also target skeletal muscle and (c) a reversible myopathy, unlike many hereditary muscle diseases. A clearer understanding of the mechanisms responsible for alcoholic myopathy is important since some of the underlying pathways may be common to other myopathies.
She's like a veal.
Could she be any more obvious about fishing for compliments on her legs?
Yeah, but how many inches is that black hairy thang?
22 lbs? Geezus. She's gonna kill it just like she killed 6iahca by overfeeding it.
Who the fuck is 6iahca
Is that a ruffled denim mini??
You better hush or you're going to lose that other eye sister.
Oh, what does it matter?
6iahcal is a special hot sauce found in Mexico. It's great on cat food.
I'm sure her knees are shot too......
What happened to her knees
We all know how beefy and thick her legs are.
All legs look like that when your feet are up on the coffee taboe, dumb bitch...but nice try with the fishing for compliments.
I have no idea how thick her legs are if I'm being honest
That cat is beautiful.