News Cure to aging might have been found..

Discussion in 'The Howard Stern Show' started by chapped, Apr 24, 2016.

  1. chapped

    chapped Well-Known Member

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    First gene therapy successful against human aging
    research news
    APRIL 22, 2016

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    Older hands. Credit: Simon Evans / flickr
    BioViva USA Inc. Elizabeth Parrish received two of her own company's experimental gene therapies: one to protect against loss of muscle mass with age, another to battle stem cell depletion responsible for diverse age-related diseases and infirmities.



    The treatment was originally intended to demonstrate the safety of the latest generation of the therapies. But if early data is accurate, it is already the world's first successful example of telomere lengthening via gene therapy in a human individual. Gene therapy has been used to lengthen telomeres before in cultured cells and in mice, but never in a human patient.

    Telomeres are short segments of DNA which cap the ends of every chromosome, acting as 'buffers' against wear and tear. They shorten with every cell division, eventually getting too short to protect the chromosome, causing the cell to malfunction and the body to age.

    In September 2015, telomere data taken from Parrish's white blood cells by SpectraCell's specialized clinical testing laboratory in Houston, Texas, immediately before therapies were administered, revealed that Parrish's telomeres were unusually short for her age, leaving her vulnerable to age-associated diseases earlier in life.

    In March 2016, the same tests taken again by SpectraCell revealed that her telomeres had lengthened by approximately 20 years, from 6.71kb to 7.33kb, implying that Parrish's white blood cells (leukocytes) have become biologically younger. These findings were independently verified by the Brussels-based non-profit HEALES(Healthy Life Extension Company), and the Biogerontology Research Foundation, a UK-based charity committed to combating age-related diseases.

    Parrish's reaction: "Current therapeutics offer only marginal benefits for people suffering from diseases of aging. Additionally, lifestyle modification has limited impact for treating these diseases. Advances in biotechnology is the best solution, and if these results are anywhere near accurate, we've made history", Parrish said.


    Bioviva will continue to monitor Parrish's blood for months and years to come. Meanwhile, BioViva will be testing new gene therapies and combination gene therapies to restore age related damage. It remains to be seen whether the success in leukocytes can expanded to other tissues and organs, and repeated in future patients. For now all the answers lie in the cells of Elizabeth Parrish, 'patient zero' of restorative gene therapy.

    Since her first gene therapy injections BioViva has received global interest from both the scientific and investment communities. Earlier this month BioViva became a portfolio company of Deep Knowledge Life Sciences (DKLS), a London-based investment fund which aims to accelerate the development of biotechnologies for healthy longevity.

    Dmitry Kaminskiy, founding partner of DKLS, said "BioViva has the potential to create breakthroughs in human gene therapy research, while leapfrogging companies in the biotech market."


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  2. Dorb

    Dorb Lovable Old Pig VIP Gold

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    Started taking niacin a few years ago for high cholesterol. Niacin also has the effect of preventing telomeres from shortening. Amazingly my almost 72 year old dick has sprung back to life.:D
     
  3. Sickboy

    Sickboy Latverian Monarch

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    Flawed reasoning in my opinion. Telomere length does not equate to youth. A more important study would be to equate diseases associated with aging as directly linked to the shortening of telomeres.
     
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  4. Rum Balls

    Rum Balls Well-Known Member

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    Me? I'm 300 years old, pal

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  5. MobyDick

    MobyDick Well-Known Member

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    The world is already overcrowded and there's 2.5 births for every 1 death currently.
    What we don't need is even longer lives unless you plan on colonizing other planets. This one's just about done.

     
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  6. Brokenbad

    Brokenbad Well-Known Member

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  7. agnes

    agnes Well-Known Member

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    Imagine wanting to live forever. I think I'd throw in the towel eventually
     
  8. Fillmore Fingers

    Fillmore Fingers Sandy Vag Banned User

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  9. BethsBraneCell

    BethsBraneCell Sandy Cunt Banned User

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    I always thought the cure to aging was death? :dontknow:
     
  10. chapped

    chapped Well-Known Member

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    I want to live just long enough to become a burden
     
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  11. Dorb

    Dorb Lovable Old Pig VIP Gold

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    I'm already a burden..........to myself. :(
     
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  12. RenchFries

    RenchFries Official Dawgshed Dutch representative VIP

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