Be nearly as rich as Howard by Wednesday, buy the house next door, grill steaks every night, marry a hot 20 year old, play loud music on the beach and have keggers by the pool every weekend. No winning tickets sold in Powerball, jackpot shoots up to $450 million A customer purchases Powerball and Mega Millions lottery tickets in Decatur on May 17. The Powerball game is played in 43 states, the District of Columbia and the U.S. Virgin Islands. (CNN)Millions played and prayed. But no one got all the six life-changing numbers: 5, 10, 21, 34, 58 and the Powerball, 33. The next drawing will be held Wednesday, and the estimated jackpot now shoots up to $450 million. The jackpot is among the largest ever and inching closer to the biggest in Powerball history: $590.5 million won in 2013 Meanwhile, here's some mathematical reality: you never stood a chance. We know, we know -- someone may get at least a share of the prize. If not this one, then in a subsequent drawing. Chances of it being you? Virtually nonexistent. The chance of a ticket winning a Powerball jackpot is 1 in 175,223,510. Youhave a better chance of becoming an astronaut, dating a supermodel -- maybe even being attacked by a shark or struck by lightning -- simultaneously. But hey, dream on! We will, too. CNN's AnneClaire Stapleton contributed to this report

If I win I will host a fundraising party whose net proceeds go to NSAL ($0.0), just so I can be like Howard...

Three months ago my local mom and pop grocery store sold the winning MM ticket worth $250 mill.One of the employees told me the store made a million for selling the winning ticket.The owners threw the staff a pizza party to celebrate.

Pick five numbers 1 to 59 and then pick one Powerball 1 to 35 so the total number of existing combinations is: (59 choose 5)*35 = 175,223,510 So once the jackpot exceeds that amount the game is (*sort of) in your favor (If you think in terms of expected values) *the one problem is if someone else - or more - also picks the winning numbers... then you would have to split up the jackpot :-( Statistical conclusion: Not worth playing. Mexican conclusion: Oh hellllls yeah!!! I'm gonna buy me $20 worth!!! -El Rexican Resident Statistician